Dissimilarity of individual microsatellite profiles under different mutation models: Empirical approach
نویسندگان
چکیده
منابع مشابه
Dynamics of microsatellite divergence under stepwise mutation and proportional slippage/point mutation models.
Recently Kruglyak, Durrett, Schug, and Aquadro showed that microsatellite equilibrium distributions can result from a balance between polymerase slippage and point mutations. Here, we introduce an elaboration of their model that keeps track of all parts of a perfect repeat and a simplification that ignores point mutations. We develop a detailed mathematical theory for these models that exhibits...
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Mutation and migration in models of microsatellite evolution∗
Dynamic and statistical properties of generalized stepwise mutation models are described and used to compare data on human di-, tri-, and tetranucleotide polymorphisms. The time-dependent behavior of an island model with stepwise mutation is analyzed and its equilibrium properties used to estimate the product Nm of the population size and the migration rate. Population statistics are derived fr...
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ژورنال
عنوان ژورنال: Ecology and Evolution
سال: 2019
ISSN: 2045-7758,2045-7758
DOI: 10.1002/ece3.5032